ONGOING CLINICAL TRIALS

ASH IL-21 with Rituximab Poster
AACR Phase 1 interim results IL-21 with Nexavar®

For information about ongoing IL-21 clinical trials:

Phase 1/2 Study of Interleukin 21 (IL-21) in Combination With Sorafenib for Metastatic Renal Cell Carcinoma

Phase 1 Study of Interleukin 21 (IL-21) with rituximab in Patients with Non-Hodgkin's Lymphoma

Contact Information
For more information, email: clinicaltrials@zgi.com

For more information about IL-21

Product Backgrounder:
http://www.zymogenetics.com/products/interleukin-21.html

Related Press Releases:

ZymoGenetics Begins Phase 2 Clinical Trial of IL-21 in Melanoma

ZymoGenetics Presents Positive Interim Phase 1 Results for IL-21 in Combination with Rituxan(R) in B Cell Lymphoma

ZymoGenetics Reports Positive Phase 1 Results for IL-21 With Nexavar(R)

ZymoGenetics Begins Phase 1/2 Clinical Trial With IL-21 and Nexavar in Patients With Renal Cell Cancer

ZymoGenetics Begins Phase 1 Trial With IL-21 and Rituxan(R) in Patients With Non-Hodgkin's Lymphoma

ZymoGenetics Reports Encouraging IL-21 Phase 1b Results in Metastatic Melanoma and Renal Cell Cancer Presented at ASCO Meeting

FDA Grants Orphan Drug Designation to ZymoGenetics' IL-21 for Treatment of Melanoma

ZymoGenetics to Begin Clinical Study with Interleukin 21; FDA gives go ahead to proceed with Phase 1 cancer study

Scientific Publications:
http://www.zymogenetics.com/research/publication.html